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bioMérieux HVAC Retro-Commissioning & Optimization Case Study | Optimum Energy
Case Study
Pharma / Manufacturing · HVAC Optimization

bioMérieux HVAC Retro-Commissioning
& Optimization

Retro-commissioning uncovers major efficiency gains across complex lab and support spaces

LocationDurham, NC
IndustryPharma / Manufacturing
Years with Optimum5+
$236,000
Year 1 Utility Savings
$200,000
Project Cost
1,800 tons
CO₂ Avoided Year 1
0.85 yrs
Simple Payback
Project Overview

A First Step Toward Decarbonization

Optimum Energy’s Engineering Solutions team was brought in to perform retro-commissioning (RCx) and optimization as a first step toward completing bioMérieux’s decarbonization roadmap. This RCx effort spanned laboratory, administrative, warehouse, packaging, and R&D facilities across the campus.

Through a rigorous audit process, the team uncovered extensive reheat loops, simultaneous heating and cooling, sub-optimal control sequences, and hardware faults including stuck heating-water valves. With a target deadline of July 2025, the team embarked on a phased program of hardware corrections, control-logic re-sequencing, setpoint resets, and terminal-unit tuning to eliminate wasted energy while maintaining occupant comfort.

Timeline & Site Visits

A Phased, Deadline-Driven Approach

Over three site visits between April and May 2025, the OE team methodically audited, corrected, and optimized bioMérieux’s HVAC systems — repairing hardware faults first, then layering in control-logic updates and setpoint resets.

1
Phase 1

Scheduling, Setpoints & Ventilation

  • Focused on occupancy scheduling, setpoint resets, and ventilation adjustments across administrative, lab, warehouse, packaging, and R&D facilities
  • Began developing a hardware deficiency log to help bioMérieux’s facilities team track and plan replacements
2
Phase 2

Control Logic & Sequence Corrections

  • Addressed control logic errors and sequence corrections building on Phase 1 findings
  • Corrected faulty hardware including a stuck valve that had been forcing the system to compensate with excess energy
  • Reprogrammed VAV and FPVAV terminal unit sequences across all 154 units
3
Phase 3

Fine-Tuned Program Adjustments

  • Concluding visits fine-tuned program adjustments across all facilities
  • By early June, targeted HVAC systems were operating with unnecessary reheat eliminated, economizers properly sequenced, and setpoints dynamically resetting
  • Efficiency gains delivered while maintaining comfort in all building types
Issue Tracking & Troubleshooting

Hardware Faults Found & Fixed

An evolving issues log captured every actuator, valve, and sensor fault that could undermine control changes. By logging each issue with priority and status and verifying repairs via trend data, OE ensured hardware faults never undermined subsequent control optimizations.

Stuck Heating-Water Valve

Forcing continuous heating during summer months until recalibrated—one of the largest single sources of wasted energy on campus.

Simultaneous Heating & Cooling

VAV reheat coils actively heating supply air the cooling system had just conditioned, wasting energy continuously at scale across 14 AHUs and 154 terminal units.

Suboptimal Control Sequences

Aging control sequences across labs, warehouses, and administrative offices had drifted from original design intent, compounding inefficiencies throughout the campus.

Faulty Hardware

Sensor and actuator failures identified and flagged across multiple AHUs, with a structured hardware deficiency log developed for the facilities team.

Over-Ventilation

Terminal units operating beyond actual zone design loads, driving unnecessary conditioning energy and heating/cooling conflicts throughout occupied hours.

Improper Occupancy Scheduling

Zones across multiple building types lacking proper occupied/unoccupied schedules, resulting in full HVAC loads running during unoccupied periods.

Scope of Work

Five Layers of Energy Savings

🔬
Engineering Analysis

Comprehensive Engineering Analysis

Full engineering analysis of all spaces and requirements across the 295,000 sq ft pharmaceutical manufacturing campus, covering administrative, warehouse, packaging, and R&D buildings.

📋
Terminal Unit Reprogramming

Full Reprogramming of All 154 Terminal Units

Full reprogramming of all 154 terminal units (VAV and FPVAV with hot water reheat) on the JCI Metasys BAS to correct sequencing errors, eliminate simultaneous heating and cooling, and align operation with design intent.

⚙️
AHU Optimization

Air Handler Optimization Across All 14 AHUs

Optimization of all 14 single duct variable volume air handling units including supply air temperature resets, duct static pressure resets, economizer sequencing corrections, and control logic tuning.

🕐
Occupancy Schedules

Occupancy-Based Scheduling Across All Buildings

Implementation of occupancy-based schedules across all building types to reduce airflow, heating, and cooling demand during unoccupied periods — delivering ongoing savings without capital investment.

📝
Deficiency Log

Hardware Deficiency Log

Development of a structured hardware deficiency log to give bioMérieux’s facilities team a clear roadmap for tracking and planning future equipment replacements identified during the retro-commissioning process.

Results & Highlights

Verifiable Savings. Completed Ahead of Schedule.

Control tuning and hardware fixes delivered double-digit energy savings well ahead of the July 2025 deadline.

$236K

Year 1 Utility Savings

Verified first-year savings against a $200,000 project investment — a 0.85-year simple payback.

1,800

Tons CO₂ Avoided in Year 1

Immediate carbon impact supporting bioMérieux’s decarbonization roadmap without capital equipment investment.

154

Terminal Units Reprogrammed

All VAV and FPVAV terminal units corrected and re-sequenced to eliminate simultaneous heating and cooling.

14

Air Handling Units Optimized

All AHUs across the campus optimized with supply air temperature resets, static pressure resets, and corrected economizer sequencing.

Key Takeaways

Lessons That Apply Everywhere

Validate Controls Before Equipment Swaps

Major hardware conversions only pay off if existing control logic is sound. Fix the software first.

Eliminate Reheat Loops Early

Mis-sequenced or stuck heating valves wipe out downstream savings. Addressing them first unlocks everything else.

Phased, Deadline-Driven Execution

Breaking the work into discrete phases — repair → re-sequence → tune — kept the project on track for completion ahead of the July deadline.

Dynamic Resets Multiply Savings

Once hardware faults are cleared, SAT and DAP resets compound energy reductions across the entire system.

Rigorous Issue Tracking

A living hardware deficiency log with clear priorities ensures no hidden fault derails controls optimization.

Decarbonization Starts with Controls

Before any capital equipment investment, optimizing existing controls delivers immediate, verifiable savings toward sustainability goals.

By responding swiftly to bioMérieux’s decarbonization roadmap, OE uncovered and eliminated the single largest energy wasters—reheat loops and a stuck valve—before any major equipment work began. With that foundation in place, SVT adjustments, dynamic setpoint resets, and precise control re-sequencing have driven significant, verifiable energy savings.
— Optimum Energy Engineering Solutions Team
Bottom Line

The Foundation for Lasting Decarbonization

By responding swiftly to bioMérieux’s decarbonization roadmap, Optimum Energy uncovered and eliminated the single largest energy wasters—reheat loops and a stuck valve—before any major equipment work began.

With that foundation in place, SVT adjustments, dynamic setpoint resets, and precise control re-sequencing have driven significant, verifiable energy savings, ensuring that by July bioMérieux’s laboratories and support spaces operate at far higher efficiency with occupant comfort fully maintained.

This project demonstrates that the path to decarbonization doesn’t always begin with capital equipment—it begins with getting existing systems to perform the way they were designed to.